Is Implant Washing and Wound Irrigation with Rifampicin Effective for Preventing Surgical Site Infections in Lumbar Instrumentation?

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dc.authoridYilmaz, Ibrahim/0000-0003-1503-4046
dc.authoridYILMAZ, Ibrahim/0000-0003-2003-6337
dc.contributor.authorKaraarslan, Numan
dc.contributor.authorYılmaz, İbrahim
dc.contributor.authorÖzbek, Hanefi
dc.contributor.authorOznam, Kadir
dc.contributor.authorAteş, Özkan
dc.contributor.authorErdem, Ilknur
dc.date.accessioned2025-03-26T17:35:09Z
dc.date.available2025-03-26T17:35:09Z
dc.date.issued2018
dc.departmentİstanbul Esenyurt Üniversitesi
dc.description.abstractAIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant infections. MATERIAL and METHODS: A total of 166 consecutive lumbar stenosis and spondylolisthesis patients undergoing lumbar instrumentation between 2012 and 2016 were analyzed retrospectively. The patients were divided into two groups. Group I (n=85) included patients whose implants were washed with rifampicin immediately before insertion and whose surgical fields were irrigated with diluted rifampicin immediately after insertion. Group II (n=81) included the cases without rifampicin application. Both groups were matched for age, sex, body mass index, and surgical indication. The infection rates of the groups were compared during the first 2 postoperative years. RESULTS: No significant difference was found between the infection rate in Group I and Group II. Only 1 case had surgical site infection (SSI) in Group I, a rate of 1.17% (1 of 85 patients), whereas 2 patients had SSI in Group II, a rate of 2.46% (2 of 81 patients). CONCLUSION: Peroperative washing of implants with rifampicin and irrigation of the surgical field using diluted rifampicin have not been found to be significantly effective in preventing or reducing spinal implant infections. However, further studies with larger series need to be carried out to verify these results.
dc.identifier.doi10.5137/1019-5149.JTN.21341-17.2
dc.identifier.endpage909
dc.identifier.issn1019-5149
dc.identifier.issue6
dc.identifier.pmid29368319
dc.identifier.scopus2-s2.0-85057204887
dc.identifier.scopusqualityQ3
dc.identifier.startpage904
dc.identifier.trdizinid299676
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.21341-17.2
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/299676
dc.identifier.urihttps://hdl.handle.net/20.500.14704/1061
dc.identifier.volume28
dc.identifier.wosWOS:000450653000008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Neurosurgical Soc
dc.relation.ispartofTurkish Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250326
dc.subjectImplant; Infection rate; Irrigation; Spine; Rifampicin
dc.titleIs Implant Washing and Wound Irrigation with Rifampicin Effective for Preventing Surgical Site Infections in Lumbar Instrumentation?
dc.typeArticle

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