İstanbul Esenyurt Üniversitesi Kurumsal Akademik Arşivi
DSpace@Esenyurt, İstanbul Esenyurt Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The effect of treatment duration on the prognosis of adhd: a multi-center naturalistic follow-up study
(ELSEVIER IRELAND LTD, 2025) Ercan, Eyuep Sabri; Bilgic, Ayhan; Tufan, Ali Evren; Akca, Omer Faruk; Yazici, Ipek Percinel; Bilac, Oznur; Tahillioglu, Akin
Objective: This study aimed to evaluate the effect of medication duration over a 5-year period on the prognosis of Attention-Deficit/ Hyperactivity Disorder (ADHD) and the accompanying disruptive behavioral symptoms using a naturalistic methodology. Methods: The sample comprised 576 ADHD cases referred to 16 Child and Adolescent Psychiatry Clinics in 13 cities in T & uuml;rkiye, aged between 7-12 five years ago and 12-18 currently. Baseline and current Turgay DSM-IV Disruptive Behavior Disorders Rating Scale (T-DSM-IV-S) scores completed by parents were compared. Sociodemographic data, treatment processes, life events, and habits were recorded. Disorder severity and recovery levels were determined using the Clinical Global Impression Scale (CGI). Results: All current T-DSM-IV-S scores were significantly lower than the baseline scores. Longer duration of medication use, receiving psychotherapy, and higher socioeconomic status were associated with better CGI scores in the present study. However, increased baseline conduct disorder symptoms, being bullied, longer duration of Internet usage, dropping out of school, smoking, and older age were associated with worse CGI scores. Conclusion: Our study indicates that a longer duration of medication use is associated with better global improvement in children with ADHD. Better identification of the factors that may directly or indirectly affect the general improvement in ADHD cases and changing these factors may enable a more positive prognosis.
Building resilience through self-defense: the role of martial arts in enhancing psychological strength among women
(FRONTIERS MEDIA SA, 2025) Pekel, Aydin; Turan, Mehmet Behzat; Eraslan, Meric; Iqbal, Mujahid; Pepe, Osman; Yoka, Keziban; Yoka, Osman
Introduction: This study aimed to investigate differences in psychological resilience between women who participate in martial arts and those who do not, while also examining the influence of demographic and socioeconomic characteristics. Methods: A total of 802 women voluntarily participated, including 407 martial arts practitioners (Muay Thai, kickboxing, boxing, or taekwondo) and 395 women who practiced Pilates. Data were collected via an online self-report questionnaire that included the Psychological Resilience Scale and a demographic information form. Statistical analyses were conducted using descriptive statistics, independent sample t-tests, and one-way ANOVA. Results: Results showed that women engaged in martial arts demonstrated significantly higher levels of psychological resilience in the sub-dimensions of control (p < .01, d = 0.47) and challenge p < .01, d = 0.27) compared to non-practitioners. However, in the commitment sub-dimension, non-martial arts participants scored higher (p < .05, d = 0.35). Among martial artists, psychological resilience varied significantly based on age, experience of violence, and smoking status. Significant differences were found for non-martial artists according to age, educational attainment, and income level. Discussion: These findings suggest that participation in martial arts may enhance specific dimensions of psychological resilience, especially in managing stress and embracing challenges. However, it may not necessarily foster higher commitment levels.
Psychometric Properties of the Turkish Version of the Reflective Functioning Questionnaire in Men on Probation for Substance Use and a Healthy Control Group
(TURKIYE SINIR VE RUH SAGLIGI DERNEGI, 2025) Altun, Seval Birdal; Luyten, Patrick; Karabulut, Vahap; Evren, Cuneyt; Bongard, Stephan
Objective: Mentalization is defined as the capacity to reflect on one's own mental state and the mental states of others. The primary aim of this study is to translate the Reflective Functioning Questionnaire (RFQ), which measures mentalization, into Turkish and evaluate its psychometric properties. In addition, reflective capacities of male adults on probation due to substance use were investigated and compared with the control group. Methods: The questionnaire was translated into Turkish using a forward-backward-forward method and administered to 219 adults with no prior psychiatric history, as well as 205 substance-using male adults. Participants also completed a battery of self-report questionnaires measuring empathy, mindfulness, theory of mind, alexithymia, and impulsivity. Additionally, the substance-using group completed the Drug Use Disorders Identification Test to assess the severity of their drug use. Results: The results indicate configural invariance of the original two-factor structure of the RFQ across the Turkish-speaking healthy control group and substance-using male adults, as well as satisfactory reliability and construct validity for the two subscales. The reflective functioning scores of the substance-using group were not significantly different from those of the control group. Discussion: This study demonstrates the reliability and validity of the Turkish version of the RFQ. Despite no significant differences in RF scores between the groups, the findings highlight the significance of further exploring reflective functioning in individuals with substance use.
The Effect of Tension-Free Vaginal Tape Surgery on Mixed Urinary Incontinence Symptoms and Anatomical Parameters: The Role of Transperineal Ultrasonography in Follow-Up
(MARY ANN LIEBERT, INC, 2025) Dogan, Ozan; Ucar, Elif; Aliyeva, Aygul; Yassa, Murat
Objective: Tension-free vaginal tape (TVT) in patients with mixed urinary incontinence (MUI) operation was aimed to show the changes in stress and urge incontinence symptoms and quality of life.Materials and Methods: This prospective study included 36 patients with MUI who underwent TVT operation. Bladder neck descent, retrovesical angle, pubourethral distance, urethral thickness, detrusor thickness, bladder, rectum, and uterus descent, and urethral rotation angle were evaluated preoperatively and 2 years postoperatively by transperineal ultrasonography, and Pelvic Organ Prolapse Quantification staging was performed. Preoperative and postoperative international consultation on incontinence questionnaire short form (ICIQ-SF) and overactive bladder questionnaire (OAB-V8) questionnaires were also performed.Results: The mean ICIQ-SF questionnaire score decreased from 16.39 preoperatively to 5.28 postoperatively. Urge symptoms assessed by the OAB-V8 questionnaire improved compared with the preoperative period (mean scores were 29.22 and 9, respectively). Nocturia mean score decreased from 2.31 to 0.81, while nocturnal voiding rates improved significantly (mean scores were 3.39 and 1.14, respectively). It was statistically proven that the effects of urinary incontinence on overall quality of life decreased after TVT (mean scores were 7.72 and 2.57, respectively). Furthermore, the mean score of bladder neck descent was 33.27 +/- 3.90 preoperatively and 17.19 +/- 3.91 postoperatively; the mean score of pubourethral distance was 12.11 +/- 1.95 preoperatively and 7.83 +/- 1.32 postoperatively; the mean score of urethral thickness was 8.69 +/- 1.58 preoperatively and 5.08 +/- 1.05 postoperatively; the mean score of detrusor thickness was 7.28 +/- 1.52 preoperatively and 4.92 +/- 1.02 postoperatively. A statistically significant difference was found between the mean scores of these parameters. In addition, retrovesical angle and urethral rotation angles decreased below the cut-off value postoperatively.Conclusions: In patients who underwent TVT for stress incontinence, if voiding functions can be restored to near normal, urge and stress symptoms improve.
Determination of Biotin Interference in Pediatric Obesity Related ELISA Research Kits Biotin Interference in Manual ELISA Kits
(WILEY, 2025) Kurkcu Kahraman, Ezgi; Donma, Orkide; Donma, Mustafa Metin; Yilmaz, Ahsen; Guzel, Savas
BackgroundAlthough high-dose biotin interference in automated immunoassays is now considered, there are very few studies showing biotin interference in manually operated research kits, especially with enzyme-linked immunosorbent assay (ELISA). The aims of our study were to determine the effects of biotin interference on various parameters, including leptin, leptin receptor (LEPR), ghrelin, acylated ghrelin, deacylated ghrelin, ghrelin receptor (GHSR), kisspeptin (KISS1), kisspeptin receptor (KISS1R), preptin, peroxisome proliferator activated receptor gamma (PPAR gamma), nod-like receptor pyrin domain-containing 3 (NLRP3) and interleukin-18 (IL-18), which contribute to energy homeostasis in healthy and obese children.MethodsSerum pools were prepared from healthy and obese individuals, and biotin concentrations in samples containing different amounts of biotin were measured via sandwich and competitive ELISA methods. In addition, possible biotin interactions were investigated by determining the concentrations of all the study parameters in serum pools containing different amounts of biotin.ResultsWe found that the biotin-competitive, ghrelin-competitive, KISS1-competitive, GHSR, leptin and LEPR ELISA kits were less affected by biotin interference and the results of these assay kits were more reliable. Unexpectedly, high levels were also measured in the biotin sandwich ELISA kit, indicating that biotin interference can also occur in manually operated assay kits.ConclusionsBiotin exhibited an interference effect even in well-functioning, qualified kits, and this negative effect was less common in competitive kits. Biotin interference was closely associated with the quality of the research kit, the parameters studied, and the presence of high biotin concentrations in the blood.
