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  • Öğe
    An Investigation into the Ability of a Solar Photovoltaic-Hydrogen System to Meet the Electrical Energy Demand of Houses in Different Cities in Türkiye
    (MDPI, 2025) Özçelep, Yasin; Bekdaş, Gebrail; Apak, Sudi; Geem, Zong Woo
    In this study, the annual electricity consumption of nine real houses from different cities in T & uuml;rkiye was recorded on a monthly basis. The feasibility of meeting the electrical energy needs of houses with hydrogen and supplying the energy required for hydrogen production using solar panels is examined. The annual electricity consumption of the houses was normalized based on house size. The solar panel area for hydrogen production needed for these houses was defined. Additionally, it was calculated that the average volumetric amount of hydrogen produced per hour during peak sun hours in the investigated cities was 1 m3/h. This approach reduced the solar panel area for hydrogen production by a factor of 1.7.
  • Öğe
    Use of the UPOINT Classification in Turkish Chronic Prostatitis or Chronic Pelvic Pain Syndrome Patients
    (Elsevier Science Inc, 2016) Arda, Ersan; Çakıroğlu, Basri; Taş, Tuncay; Ekici, Sinan; Uyanik, Bekir Sami
    OBJECTIVE To determine the positive subdomain numbers and distribution of the UPOINT classification in chronic prostatitis and to compare the erectile dysfunction (ED) pattern. MATERIALS AND METHODS From 2008 to 2013, 839 patients with symptomatic chronic prostatitis or chronic pelvic pain syndrome were included in this study. The correlation between UPOINT domains and National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) total score, subscores, and the 5-item International Index of Erectile Function scores were evaluated retrospectively. RESULTS The mean patient age was calculated as 37.7 +/- 7.4 (range 21-65). The average total NIH-CPSI score was determined as 9.07 (range 1-40) and the average positive UPOINT subdomain number was determined as 2.87 +/- 0.32 (range 1-6). Subdomain patient numbers and rates were calculated as 529 urinary (63%), 462 psychosocial (55%), 382 organ specific (45%), 290 infection (34%), 288 neurological or systemic (34%), and 418 tenderness (skeletal muscle) (50%), respectively. It was determined that ED, determining the subdomain of sexual dysfunction in patients, was positive in a total of 326 (39.9%) patients, with 220 patients having mild (26.2%), 76 mild to moderate (9.1%), 19 moderate (2.3%), and 5 with severe (0.6%) ED. A statistically significant correlation was not determined between the 5-item International Index of Erectile Function score and UPOINT subdomain number and NIH-CPSI score. CONCLUSION It has been determined that although there is a strong and significant correlation between UPOINT classification and NIH-CPSI score in Turkish patients with chronic prostatitis or chronic pelvic pain syndrome, the inclusion of ED as an independent subdomain to the UPOINT classification is not statistically significant. (C) 2016 Elsevier Inc.
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    The role of masonry infills on the interstory drift demand of reinforced concrete frames
    (Elsevier Sci Ltd, 2024) Etemadi, Ali; Balkaya, Can
    Most frame buildings, especially those with shear -type moment resistance frames, are affected by masonry infill panels, which change the mechanical properties of whole systems in a big way. In turn, seismic performance varies depending on the infill panel and frame interactions. In conventional structural design practice, such interaction has been overlooked. This study looks at the range of local displacement demands in shear -type frames with and without infill panels. Generic frames are developed by tuning the story stiffness and mass to produce a reasonable period range between 0.2 and 2.0 s. The masonry infill panels are simulated through equivalent diagonal struts. A Bouc-Wen-based hysteretic model is applied to incorporate the post -yielding hysteresis degradations of both columns and masonry panels. The hysteresis loop control parameter values are also given for incorporating masonry infill properties. The correlation analysis between the strength and stiffness of RC frames and masonry infills is supplied as an instrument for calibrating the hysteretic model. In the collection of records, there are a lot of near -fault ground motions, which puts a lot of seismic demands on the buildings. The modification factors via regression analysis are proposed using over 1254 nonlinear response history analyses. This modification factor is figured out by looking at the difference between the mean drift spectrum for a set of generic frames that are both bare and filled. The nonlinear analysis shows that residual drift demands can be reduced in the case of panel effects that exist for masonry-infilled mid -rise RC shear -type frames.
  • Öğe
    Evaluation of extractability of 2,4,6-trinitrophenol by secondary amine extractant in alcohols: Equilibrium and molecular dynamic study
    (Elsevier, 2017) Uslu, Hasan
    Extractive separation of 2,4,6-trinitrophenol (picric acid, PAH) from its aqueous solutions was examined at constant temperature of 298.2 K. The experiments were studied on the extraction of PAH (0.061 mol kg(-1)) by Amberlite LA2, a secondary amine diluted in five different alcohols such as isopropyl alcohol, isoamyl alcohol, hexanol, heptanol, and decanol. In addition to reactive extraction, experiments on physical extraction were also performed by pure diluents. Experimental results obtained from batch extraction were evaluated in terms of distribution coefficients (K-D), extraction efficiency (E), and loading factors (Z). The highest synergistic effect was achieved with isopropyl alcohol in LA-2 at a concentration of 0.588 mol kg(-1) as 98.36%. The highest value of probable equilibrium constants for the complex between acid and amine (1:1), K-11 was calculated to be 11.62 for isopropyl alcohol at 0.588 mol kg(-1) LA-2 concentration. Kinetic and potential energies of components during reactive extraction in the organic phase have been determined by molecular dynamic modeling for picric acid + isopropyl alcohol + secondary amine. The values of energy, per atom, for mixture picric acid + isopropyl + secondary amine were respectively: similar to 30,000 kcal/mol, similar to 15,000 kcal/mol, similar to-50,000 kcal/mol and similar to-60,000 kcal/mol. (C) 2016 Elsevier B.V. All rights reserved.
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    Separation of Levulinic Acid Using Polymeric Resin, Amberlite IRA-67
    (Amer Chemical Soc, 2019) Uslu, Hasan; Datta, Dipaloy; Santos, Dheiver; Öztürk, Muhsin
    The adsorptive separation of levulinic acid (LA) from its aqueous solution was studied by using a commercial adsorbent and weakly basic anion exchange resin, Amberlite IRA-67 (IRA-67). The data were generated for equilibrium and kinetic studies, and to analyze the performance of IRA-67 on the removal efficiency. The equilibrium study was performed to see the effect of adsorbent quantity (0.25-1.5 g) and initial LA concentrations (2-4 g.L-1) at three different temperatures (298, 308, and 318 K). To determine the kinetics of adsorption process, concentration profile was achieved up to a time of 90 min at 298 K. It was observed that both the intake capacity (32-64 mg.g(-1)) and removal efficiency (6.75-72.5%) of IRA-67 were increased with an increase in the quantity of adsorbent (0.25-1.5 g) at 298 K. From the kinetics of adsorption, 50 min was considered as an equilibrium time. Different isotherm and kinetic models were used to determine the equilibrium and kinetic parameters of LA adsorption process. From the temperature study (298, 308, and 318 K), the thermodynamic properties were also estimated at three different LA concentrations.
  • Öğe
    Constitutive Model and Mechanical Properties of Grade 8.8 and 10.9 High-Strength Bolts at Elevated Temperatures
    (Asce-Amer Soc Civil Engineers, 2024) Saglik, Huseyin; Etemadi, Ali; Chen, Airong; Ma, Rujin
    This paper presents an experimental study on the determination of the mechanical behaviors of Grade 8.8 and 10.9 high-strength bolts at elevated temperatures. Strength reduction coefficients are obtained based on test results at temperatures ranging from 20 degrees C to 900 degrees C, for both yield and ultimate stresses. Simplified expressions are presented to identify the strength reduction factors at considered temperatures. At 400 degrees C, the yield and ultimate strengths of bolts decrease by 30%-35% for both grades compared to those in ambient temperature. Yield strengths are 30% and 20% of yield strengths of Grade 8.8 and 10.9 bolts at ambient temperature, respectively, when the temperature exceeds 500 degrees C. The ultimate strength decreases slightly slower than the yield strength at high temperatures. Although the decrease in ultimate strength follows the decrease in yield strength at elevated temperatures, it is slightly slower. About 3%-6% of yield and ultimate strengths at ambient temperature remain for both grades at 700 degrees C. Moreover, a series of expressions are provided to obtain the full range stress-strain curve of high-strength bolts at elevated temperatures. Comprehensive literature studies are taken into consideration to propose a more generalized description of the stress-strain curves. The proposed model can be fully drawn by only using elastic modulus, yield, and ultimate stresses at ambient temperature. It is shown that the proposed model has enough efficiency to describe the general material behavior at elevated temperatures.
  • Öğe
    Equilibrium Data on the Reactive Extraction of Picric Acid from Dilute Aqueous Solutions Using Amberlite LA-2 in Ketones
    (Amer Chemical Soc, 2017) Uslu, Hasan; Marti, Mustafa Esen
    The present study is on the reactive extraction of picric acid (HPc, 2,4,6-trinitrophenol) from dilute aqueous solutions by organic phases containing Amberlite LA-2 (ALA 2) as extractant dissolved in four types of ketones. The studies were performed at 298, 308, and 318 K, and the results were used to calculate the values of distribution coefficient (KD), loading factor (Z), and degree of extraction (E%). Initial HPc concentration was kept constant at 0.061 mol.kg(-1). The maximum KD was obtained as 60 using methyl ethyl ketone when initial concentrations of PA and ALA-2 were 0.061 and 0.59 mol.kg(-1), respectively. The extraction efficiency was 98.36% under these conditions. Moreover, z-values between 0.09 and 0.27 were obtained in the ranges of parameters studied. Calculated values show that 1:2 picric acid-ALA-2 complex dominates the extraction process.
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    Comparison of antagonist mild and long agonist protocols in terms of follicular fluid total antioxidant capacity
    (Elsevier Taiwan, 2018) Mathyk, Begum Aydogan; Cetin, Berna Asian; Vardagli, Duygu; Zengin, Emel; Sofiyeva, Nigar; Irez, Tulay; Ocal, Pelin
    Objective: A high dose of prolonged gonadotropins can yield higher numbers of oocytes and embryos. The high dose or prolonged regimens can be associated with ovarian hyperstimulation syndrome (OHSS), multiple gestations, emotional stress, economical burden and treatment dropout. In mild stimulation lower doses and shorter duration times of gonadotropin are used in contrast to the conventional long stimulation protocol in IVF. It has been proposed that supraphysiologic levels of hormones may adversely affect endometrium and oocyte/embryo. Also it has been proposed that oxidative stress (OS) may alter ovarian hormone dynamics and could be further affected by additional exogenous hormonal stimulation. Therefore our aim was to compare follicular fluid total antioxidant capacity (TAC) in antagonist mild and long agonist stimulations. Materials and Methods: Forty patients received antagonist mild stimulation, starting on the 5th day of their cycle and forty patients received long agonist treatment. Seventy-five patients undergoing their first IVF cycle were included in the final analysis. Follicular fluid (FF) samples were analyzed for estradiol (E2), antimullerian hormone (AMH) and TAC. Results: FF-Total antioxidant capacity (TAC) levels were higher in the long agonist group as opposed to the antagonist group [1.07 +/- 0.04 mmol Trolox equivalent/L vs 1 +/- 0.13 mmol Trolox equivalent/L] (Fig. 1). Pregnancy rates were not significantly different between the two treatments. The FF-TAC levels were not different among infertility etiologies (Fig. 3). FF-TAC levels did not have a direct correlation with pregnancy but a positive correlation with the total gonadotropin dose was observed. Conclusion: Patients with good ovarian reserves and under the age of 35 effectively responded to mild stimulation treatment. Using lower amounts of gonadotropin, yielded less FF-TAC levels in patients who underwent antagonist mild protocol. In patients under the age of 35, antagonist mild stimulation is a patient friendly and effective procedure when undergoing their first IVF cycle. (C) 2018 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.
  • Öğe
    Solvent Polarity Effect when Amberlite-LA2 Is Used in the Extraction of Picric Acid
    (Amer Chemical Soc, 2017) Uslu, Hasan; Datta, Dipaloy; Bamufleh, Hisham S.
    The separation and recovery of picric acid (0.061 mol-kg(-1)) from its aqueous solution was studied at a fixed temperature of 298 K. The extraction experiments were performed by using a secondary amine, Amberlite-LA2 (ALA2), dissolved in five different solvents such as dichloromethane (DCM), dodecanol, toluene, benzene, and dodecane. Physical extraction data were also produced by pure solvent alone. The experimental data obtained from the batch studies were analyzed by calculating the distribution coefficient (K-D), extraction efficiency (%E), and loading factor (Z). The highest synergistic effect was achieved with DCM in ALA2 at a concentration of 0.588 mol.kg(-1) as 83.61%. The equilibrium constants for the complex formation between acid and amine (1:1 and 2:1) were calculated for all the solvents applying the mass action law.
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    Zn2+ Ion Adsorption from Aqueous Solution Using Montmorillonite Clay Impregnated with Tri-n-octylamine
    (Amer Chemical Soc, 2017) Uslu, Hasan; Datta, Dipaloy; Bamufleh, Hisham S.
    Montmorillonite (Mt) clay was used to remove zinc (Zn2+) ion from the aqueous solution. This clay material was modified (Mt-TOA) by impregnating trin-octylamine (TOA), a tertiary amine. The experiments on equilibrium and kinetics were done to analyze the effect of adsorbent amount (w, 0.05 to 0.3 g for Mt, 0.01 to 0.06 g for Mt-TOA), initial Zn2+ ion concentration (C-0, 15 mg.L-1 to 35 mg.L-1), pH (1 to 9), and contact time (t, 0 to 100 min) on the efficacy of both adsorbents. With a greater amount of adsorbent, the intake capacity of Mt and Mt-TOA for Zn2+ ion removal was found to lower but there was an increase in the separation efficiency. The optimum amount of Mt and Mt-TOA was found to be 0.1 and 0.01 g, respectively. The pH of the aqueous solution could be maintained at 7 to achieve a better adsorption of Zn2+ ion. In the kinetic experiments, after 90 min, the separation efficiency of Zn2+ ion from aqueous solution reached to a value of 86.68% with Mt (0.1 g) and 84.56% with Mt-TOA (0.01 g). Modeling of the equilibrium and kinetic data were done by using the Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich, and by using the pseudo-first-order, pseudo-second-order, and intraparticle diffusion models, respectively, and the best fitted model is presented.
  • Öğe
    Adsorptive Separation of Lead (Pb2+) from Aqueous Solution Using Tri-n-octylamine Supported Montmorillonite
    (Amer Chemical Soc, 2017) Datta, Dipaloy; Uslu, Hasan
    Divalent lead present in the water stream was removed by using adsorption techniques with montmorillonite clay (Mt) modified with tri-n-octylamine (Mt-TOA). Batch adsorption data at equilibrium were determined with different initial Pb2+ ions concentration (8, 10, 12, 14, and 16 mg.L-1) in the aqueous solution at 298 K, and these results were correlated by using three different isotherm models, for instance, the Langmuir, the Freundlich, and the Temkin. The two-parameter Langmuir model was the best fit to the equilibrium data with a coefficient (R-2) greater than 0.99. The maximum capacities for monolayer adsorption of Mt and Mt-TOA were determined to be 3.37 mg.g(-1) and 33.1 mg.g(-1), respectively, as estimated from Langmuir. Also, experimental values were generated to evaluate the influence of adsorbent amount (w, 0.05-0.3 g for Mt, 0.01-0.06 g for Mt-TOA), starting Pb2+ ion concentration (C-0,8 mg.L-1 to 16 mg.L-1), pH (between 1 and 9), and contact period (t, from 10 to 110 min) on the removal effectiveness and adsorption capability of Mt and Mt-TOA adsorbents. In respect to kinetic studies, the removal efficiency of Pb2+ ion reached to a fixed value of 81.42% with Mt (0.1 g) and 80.67% by Mt-TOA (0.01 g) next 100 and 80 min, respectively. Pseudo-first order, pseudo-second order, and intraparticle diffusion models were studied to obtain the kinetic parameters of the adsorption practice. It is observed that the rate of mass transfer of Pb2+ ions was mainly governed by the intraparticle diffusion mechanism.
  • Öğe
    Adsorption Studies of Lactic Acid by Polymeric Adsorbent Amberlite XAD-7: Equilibrium and Kinetics
    (Amer Chemical Soc, 2017) Uslu, Hasan; Majumder, Subhajit
    The present study deals with the separation of lactic acid (LA) by a polymeric adsorbent Amberlite XAD-7. Equilibrium and kinetic studies were carried out to investigate adsorption of LA on Amberlite XAD-7 at three different temperatures (298, 308, and 318 K). Equilibrium studies revealed the optimum dose of Amberlite XAD-7 as 2.5 g. The adsorption equilibrium time was determined as 90 min. Adsorption isotherms such as Freundlich, Langmuir, Temkin, and Dubinin-Radushkevich were validated using the obtained experimental data. Langmuir isotherms showed better fitting with the experimental data with R-2 = 0.99. Pseudo-second-order model and Elovich model were used to fit the adsorption system. Study also revealed 99% removal of LA using Amberlite XAD-7.
  • Öğe
    Extraction of Citric Acid and Maleic Acid from Their Aqueous Solutions Using a Phosphorus-Bonded Extractant, Tri-&ITn&IT-octylphosphineoxide, and a Secondary Amine, Dioctylamine
    (Amer Chemical Soc, 2018) Hasret, Erdem; Kirbaslar, Sah Ismail; Uslu, Hasan
    The aim of this study is to investigate the extraction of citric acid and maleic acid from their aqueous solutions using different solvent-extractant mixtures in order to find the most effective composition for the extraction. Citric and maleic acids are chosen as the carboxylic acids due to their commercial worth in the industrial processes. Carboxylic acids are recovered from their aqueous solutions by reactive extraction, a promising liquid-liquid extraction technique, using trioctylphosphineoxide (TOPO), and a secondary amine called dioctylamine (DOA). TOPO has been chosen as an extractant since it has low water solubility, high stability, and it is more environmentally friendly than the amine-type extractants. For other amine extractants used in reactive extraction processes, there is a lack of study in the literature about the extraction of these acids with DOA. Extractants were dissolved in nine different solvents (butanol, decanol, octanol, isoamylalcohol, octane, decane, methylisobutylketone, and diisobutylketone) having different chemical structures. All experiments were carried out at 298.15 K. Comparisons of the results were made using, the distribution coefficient (D), loading factor (Z), and the extraction yield (%E). It has been observed that a considerable amount of citric acid and maleic acid extraction was achieved using DOA (in the range of 13.95-99.19% and 31.94-99.41% according to the diluent used for citric acid and maleic acid, respectively) compared to that achieved with TOPO (in the range of 0.81-67.12% and 16.25-89.33% according to the diluent used for citric acid and maleic acid, respectively).
  • Öğe
    Is Implant Washing and Wound Irrigation with Rifampicin Effective for Preventing Surgical Site Infections in Lumbar Instrumentation?
    (Turkish Neurosurgical Soc, 2018) Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Oznam, Kadir; Ateş, Özkan; Erdem, Ilknur
    AIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant infections. MATERIAL and METHODS: A total of 166 consecutive lumbar stenosis and spondylolisthesis patients undergoing lumbar instrumentation between 2012 and 2016 were analyzed retrospectively. The patients were divided into two groups. Group I (n=85) included patients whose implants were washed with rifampicin immediately before insertion and whose surgical fields were irrigated with diluted rifampicin immediately after insertion. Group II (n=81) included the cases without rifampicin application. Both groups were matched for age, sex, body mass index, and surgical indication. The infection rates of the groups were compared during the first 2 postoperative years. RESULTS: No significant difference was found between the infection rate in Group I and Group II. Only 1 case had surgical site infection (SSI) in Group I, a rate of 1.17% (1 of 85 patients), whereas 2 patients had SSI in Group II, a rate of 2.46% (2 of 81 patients). CONCLUSION: Peroperative washing of implants with rifampicin and irrigation of the surgical field using diluted rifampicin have not been found to be significantly effective in preventing or reducing spinal implant infections. However, further studies with larger series need to be carried out to verify these results.
  • Öğe
    Prognostic Factors in Patients who Underwent Aneurysmal Clipping due to Spontaneous Subarachnoid Hemorrhage
    (Turkish Neurosurgical Soc, 2016) Orakdogen, Metin; Emon, Selin Tural; Somay, Hakan; Engin, Taner; Ateş, Özkan; Berkman, Mehmet Zafer
    AIM: Despite technical and medical advances, aneurysmal subarachnoid hemorrhages (SAH) continue to be a challenging pathology, associated with high rates of morbidity and mortality. In this regard, a definition is required of the various prognostic indicators of an SAH. The aim of the present retrospective study is to examine the various prognostic factors of the clinical outcomes of the patients who underwent a neurosurgical clipping of aneurysms due to aneurysmal SAH. MATERIAL and METHODS: The data of 104 patients that had suffered an aneurysmal SAH were analyzed. The baseline demographic, clinical and radiological data were all analyzed. The prognostic study was derived from an analysis of these variables. Relationship between prognostic factors and outcome was evaluated by univariate and logistic multivariate regression analysis. RESULTS: This study has identified unfavorable outcomes on the Glasgow Outcome Scale at discharge after the surgical treatment of aneurysmal SAH associated with increased age, poor World Federation of Neurosurgical Societies (WFNS) grade on admission, higher Fisher's grade on admission computed tomography scan, larger aneurysm, and clinical vasospasm. In a multivariate logistic regression analysis, age, high WFNS grade, positive clinical vasospasm and size of aneurysm were found to be independent risk factors for mortality. The presence of hydrocephalus, number of aneurysms, positive risk factors, and the presence of Doppler vasospasm did not reach statistical significance. CONCLUSION: The most important prognostic factors in patients undergoing surgery due to aneurysmal subarachnoid hemorrhage were WFNS grade, age, size of aneurysm and clinical vasospasm.
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    Prevalence of Staphylococcal Enterotoxins in Ready-to-Eat Foods Sold in Istanbul
    (Elsevier, 2017) Ulusoy, Beyza H.; Sancar, Burcu Cakmak; Öztürk, Muhsin
    The aim of this study was to investigate the prevalence of staphylococcal enterotoxins (SEs) in ready-to-eat (RTE) foods sold in Istanbul, Turkey. A total of 5,241 samples were randomly collected from various caterers, hotels, and restaurants from 2014 to 2016. The samples were classified into four groups: (i) various cooked RTE meat and vegetable meals, (ii) various RTE salads, charcuterie, and cold appetizers, (iii) various cooked RTE bakery products (pasta, pastries, pizza, pita, ravioli, etc.), and (iv) any cooked RTE sweets and desserts (pudding, custard, cream, ashura, etc.). The samples were examined for the presence of SEs by 3M Tecra Staph Enterotoxin Visual Immunoassay method, which is a manual enzyme-linked immunosorbent assay method. Among all samples, only 1 (0.019%) RTE meal (vegetable meal with meat) was found to be contaminated with SEs, a good result in terms of staphylococcal food poisoning risk and public health.
  • Öğe
    Are Specific Gene Expressions of Extracellular Matrix and Nucleus Pulposus Affected by Primary Cell Cultures Prepared from Intact or Degenerative Intervertebral Disc Tissues?
    (Turkish Neurosurgical Soc, 2019) Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Yasar Sirin, Duygu; Kaplan, Necati; Akyuva, Yener; Gonultas, Aylin
    AIM: To determine the gene expression patterns of nucleus pulposus (NP) in cell cultures obtained from degenerated or intact tissues. MATERIAL and METHODS: Whereas 12 of the cases were diagnosed with lumbar disc herniation and had undergone lumbar microdiscectomy, 12 cases had undergone traumatic intervertebral discectomy and corpectomy, along with discectomy after spinal trauma. NP-specific markers and gene expressions of the reagents of the extracellular matrix in the experimental setup were tested at the 0th, 24th, and 48th hours by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). Visual evaluations were simultaneously made in all samples using invert and fluorescence microscopy. Vitality and proliferation analyses were evaluated by UV spectrophotometer. As a method of statistical evaluation, Spearman was used for categorical variants, and the Pearson correlation was used for variants with numerical and plain distribution. RESULTS: No association was found either between the tissue type and times (r=0.000; p=1.000) or between the region that the tissue was obtained from and hypoxia transcription factor-1 alpha (HIF-1 alpha) gene expression (r=0.098; p=0.245). There was no correlation between cell proliferation and chondroadherin (CHAD) expression or between type II collagen (COL2A1) and CHAD gene expressions. It was found that CHAD and HIF-1 alpha gene expressions and HIF-1 alpha and COL2A1 gene expressions affected cell proliferation. CONCLUSION: Cell culture setups are of paramount importance because they may influence the pattern of changes in the gene expressions of the cells used in these setups.
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    Meeting the electricity demand for the heating of greenhouses with hydrogen: Solar photovoltaic-hydrogen-heat pump system application in Turkey
    (Pergamon-Elsevier Science Ltd, 2023) Ozcelep, Yasin; Bekdas, Gebrail; Apak, Sudi
    Providing the heating system with coal in greenhouses causes harmful results in terms of carbon emissions. In this study, analyzes were performed to meet the electrical energy required for the heating system with a heat pump from a solar photovoltaic-hydrogen system. For floor area 25000 m2 where greenhouses the required energy is obtained directly from hydrogen without using a heat pump 3000 m2 solar panel area required. The use of a heat pump reduces energy needs but it is also not feasible for large greenhouses. For convenience, a solar photovoltaic-hydrogen-heat pump system analysis was also made for 1000 m2 floor area greenhouses and it is found that the 24 m2 solar panel area is adequate in terms of meeting energy demand. Using a solar-hydrogen-heat pump system reduces carbon emissions by 86.5 tons per 1000 m2 floor area greenhouse. Considering the hydrogen storage system becomes unfeasible. We normalized the greenhouse floor area to 1 m2 and proposed reference values for hydrogen to be produced in 1 h, storage, and PV area. In addition, an analysis was made for the use of hydrogen energy for greenhouses that do not require a heating system and only work with a water pump. (c) 2022 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.
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    Enhancing the Functionality and shelf life of poppy sherbet by optimizing ultrasound and propolis using response surface methodology: Impact on phenolic compounds, organic acids, sugar components, and sensory characteristics
    (Elsevier, 2025) Akhan, Meryem; Turkol, Melikenur; Yikmis, Seydi; Sancar, Burcu cakmak; Col, Basak Gokce; Khalid, Muhammad Zubair; Moreno, Andres
    Poppy plant, scientifically known as Papaver rhoeas L., is an annual herbaceous wild plant. Propolis boasts numerous health advantages. This study aimed to optimize a novel functional beverage enriched with propolis and enhanced with ultrasound technology using Response Surface Methodology (RSM). Optimization focused on total bioactivities and general acceptability, determining optimal amounts of propolis extract (53.33 mg/100 mL), ultrasound time (7.56 min), and ultrasound amplitude (75.76%) to create the optimized ultrasound-treated propolis poppy sherbet (UTP). The optimized UTP had a high total phenolic content (552.25 mg GAE/L), a DPPH value of 9.26 mu mol trolox/g, a total antioxidant capacity of 42.16 mg Cy-3-gly/mL (Cyanidine-3-glycoside/mL), and a general acceptability score of 7.87. The consistency between experimental results and RSM predictions confirmed the approach's accuracy. After 21 days, bioactive components, phenolic compounds, organic acids, sugars, and sensory properties were assessed. UTP showed enhanced bioactive components and sensory properties compared to standard poppy sherbet, with higher glucose and turanose among 17 phenolic compounds. However, sensory attributes like color, aroma, and taste significantly declined over storage. As a result, these findings contribute to the development of functional beverages and the further enhancement of poppy-related foods using RSM optimization.
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    Rehabilitation of Patients With Osteoporotic Fractures
    (Elsevier Science Inc, 2020) Erhan, Belgin; Ataker, Yaprak
    Osteoporosis is a silent, asymptomatic disease until a fragility fracture is sustained. Fractures greatly affect the physical functioning and health-related quality of life and are associated with increased mortality and mor-bidity rates. Furthermore, once a fragility fracture occurs, the patient is more susceptible to sustain further fractures. Repeated falls are the main causes of fractures in patients with osteoporosis. The management of osteoporosis postfracture is a combination of medical treatment, nutritional interventions, and rehabilitation in order to improve activities of daily living to prevent falls and increase safety while reducing the loss of bone mass. In this article the principles of fracture prevention and physical rehabilitation of patients with osteoporosis postvertebral and hip fragility fractures will be discussed, as well as the rehabilitation management to prevent further falls and fractures.