Habitual Caffeine Consumption and Training Status Affect the Ergogenicity of Acute Caffeine Intake on Exercise Performance

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dc.authoridDemirli, Abdullah/0000-0003-1727-4596
dc.authoridKhodadadi, Davar/0000-0003-0546-6515
dc.authoridJalali, Parham/0000-0003-3661-3995
dc.authoridEGHBAL MOGHANLOU, Abdorreza/0000-0003-1238-0541
dc.contributor.authorKhodadadi, Davar
dc.contributor.authorAzimi, Farhad
dc.contributor.authorMoghanlou, Abdorreza Eghbal
dc.contributor.authorGursoy, Recep
dc.contributor.authorDemirli, Abdullah
dc.contributor.authorJalali, Parham
dc.contributor.authorBehdari, Reza
dc.date.accessioned2025-03-26T17:34:56Z
dc.date.available2025-03-26T17:34:56Z
dc.date.issued2025
dc.departmentİstanbul Esenyurt Üniversitesi
dc.description.abstractBackground: Acute caffeine ingestion can improve exercise performance. Interplay between caffeine habituation and training status on the performance-enhancing effect of caffeine is unknown. Hypothesis: Habitual caffeine consumption and training status affect the ergogenicity of pre-exercise caffeine intake on exercise performance. Study Design: Double-blind, placebo-controlled, counterbalanced experimental design. Level of Evidence: Level 3. Methods: Eighty physically inactive men were randomized into 1 of 4 groups: caffeine supplementation (CAF), caffeine supplementation + exercise training (CAFEXE), placebo (PLA), and placebo + exercise training (PLAEXE); high-intensity interval training and caffeine were administered for 9 and 8 weeks, respectively. Data were collected pre-test, mid-test, post-test, and delayed post-test, each including 2 experiment sessions (3 mg/kg caffeine or placebo), with an additional experiment session post-test (6 mg/kg caffeine). In each experiment session, 45-min after consuming a placebo or caffeine, a 3-km running test and a Wingate power test were performed. Results: Pre-exercise ingestion of 3 mg/kg caffeine improved 3-km running time and mean power output (MPO) in all groups at all stages (P < 0.05); this effect was higher in trained than in untrained volunteers (P < 0.05). Habitual caffeine consumption reduced the ergogenic effect of caffeine in both aerobic and anaerobic trials (P < 0.05); 6 mg/kg caffeine enhanced this decrease only in CAFEXE (P < 0.05). Short-term caffeine withdrawal augmented the reduced ergogenic effect of caffeine on 3-km running performance and MPO in CAF and CAFEXE (P < 0.05). Conclusion: Habituation to caffeine and training status could partially influence the ergogenic effects of caffeine on exercise performance.
dc.identifier.doi10.1177/19417381251315093
dc.identifier.issn1941-7381
dc.identifier.issn1941-0921
dc.identifier.pmid39905628
dc.identifier.scopus2-s2.0-85217010023
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1177/19417381251315093
dc.identifier.urihttps://hdl.handle.net/20.500.14704/944
dc.identifier.wosWOS:001414731800001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofSports Health-A Multidisciplinary Approach
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250326
dc.subjectcaffeine habituation; ergogenic aid; exercise performance; high-intensity interval training; training status
dc.titleHabitual Caffeine Consumption and Training Status Affect the Ergogenicity of Acute Caffeine Intake on Exercise Performance
dc.typeArticle

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