The role of serum acute phase reactant levels in the prediction of impacted ureteral stone

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dc.contributor.authorHazar, Ismet Aydin
dc.contributor.authorTaş, Tuncay
dc.contributor.authorGezmis, Cem Tugrul
dc.contributor.authorArda, Ersan
dc.contributor.authorCilesiz, Nusret Can
dc.contributor.authorÇakıroğlu, Basri
dc.date.accessioned2025-03-26T16:10:01Z
dc.date.available2025-03-26T16:10:01Z
dc.date.issued2019
dc.departmentİstanbul Esenyurt Üniversitesi
dc.description.abstractObjectives: The aim of this study was to investigate the determination of ureteral stone impaction using acute phase reactants. Methods: A total of 110 patients who had a single ureteral stone treated during a single month using medical expulsive therapy of tamsulosin 0.4 mg/day, diclofenac 75 mg upon analgesic requirement, and at least 3 liters fluid per day were evaluated prospectively. The patients underwent ureteroscopy and were divided into 2 groups according to the pres-ence or absence of impaction. The preoperative white blood cell (WBC) count, red blood cell distribution width (RDW), C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), mean platelet volume (MPV), and neutrophil-to-lymphocyte ratio (NLR) in the non-impacted stone group (Group 1; n=59) and the impacted group (Group 2; n=51) were statistically compared. Results: There was no statistically significant difference in terms of age, stone diameter, body mass index, grade of hy-dronephrosis, or stone localization between the 2 groups. The WBC, RDW, and MPV value differences were statistically significant between the groups (p=0.035, p=0.035, and p=0.005, respectively). An MPV cut-off value of 9.55 fL was de-fined in Group 2 with 66% sensitivity and 62% specificity for impaction. There was no statistically significant difference between the groups in CRP, ESR, or NLR values (p=0.44, p=0.76, p=0.54, respectively). Conclusion: Evaluation of serum MPV with a cut-off value of 9.55 fL may predict ureteral stone impaction. © 2019 by International Journal of Medical Biochemistry.
dc.identifier.doi10.14744/ijmb.2019.20592
dc.identifier.endpage106
dc.identifier.issn2587-2362
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85168942620
dc.identifier.scopusqualityQ4
dc.identifier.startpage102
dc.identifier.trdizinid331817
dc.identifier.urihttps://doi.org/10.14744/ijmb.2019.20592
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/331817
dc.identifier.urihttps://hdl.handle.net/20.500.14704/776
dc.identifier.volume2
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKare Publishing
dc.relation.ispartofInternational Journal of Medical Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250326
dc.subjectImpacted
dc.subjectmean platelet volume
dc.subjectred blood cell distribution width
dc.subjectureteral stone
dc.subjectwhite blood cell
dc.titleThe role of serum acute phase reactant levels in the prediction of impacted ureteral stone
dc.typeArticle

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