A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle-A Prospective Pilot Study

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dc.authoridtoprak, kenan/0000-0001-8923-8709
dc.contributor.authorUçar, Elif
dc.contributor.authorToprak, Kenan
dc.contributor.authorKaratas, Mesut
dc.date.accessioned2025-03-26T17:34:45Z
dc.date.available2025-03-26T17:34:45Z
dc.date.issued2024
dc.departmentİstanbul Esenyurt Üniversitesi
dc.description.abstractBackground and Objectives: Preeclampsia, a pregnancy-induced hypertensive disorder, shares cardiovascular characteristics in etiology, prognosis, and fetomaternal risks. Electrocardiography plays a pivotal role in assessing cardiovascular risks. Beyond conventional predictors, identifying easily obtainable and reproducible electrocardiographic markers may significantly contribute to the early identification of individuals at risk of preeclampsia. In this study, we aimed to investigate the value of the Frontal QRS-T angle and other electrocardiographic parameters in predicting the development of preeclampsia. Materials and Methods: A total of 62 pregnant patients diagnosed with preeclampsia and 50 healthy pregnant patients as the control group were included in this study. The first- and third-trimester electrocardiographic parameters were compared within groups and between groups. Results: The Frontal QRS-T angle was significantly elevated in patients with preeclampsia compared to the controls (55.0 +/- 40.8 vs. 19.5 +/- 15.1; p = 0.002). The first-trimester Frontal QRS-T angles in the patients with preeclampsia were higher than those of the controls (29.5 +/- 25.0 vs. 15.3 +/- 11.5; p = 0.015). A high Frontal QRS-T angle independently marked preeclampsia development in antenatal and late pregnancy (p = 0.003 and p = 0.042, respectively). The diagnostic accuracy of the Frontal QRS-T angle in predicting preeclampsia surpassed other electrocardiographic parameters. Conclusions: This study shows that the Frontal QRS-T angle may be a candidate to be an independent predictor for the development of preeclampsia. In this context, the Frontal QRS-T angle, which is an electrocardiographic parameter, seems promising.
dc.identifier.doi10.3390/medicina60111856
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue11
dc.identifier.pmid39597041
dc.identifier.scopus2-s2.0-85210452919
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/medicina60111856
dc.identifier.urihttps://hdl.handle.net/20.500.14704/884
dc.identifier.volume60
dc.identifier.wosWOS:001365571900001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofMedicina-Lithuania
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250326
dc.subjectelectrocardiography; Frontal QRS-T angle; preeclampsia
dc.titleA Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle-A Prospective Pilot Study
dc.typeArticle

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