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Öğe Predicting Lamina Propria Invasion in Patients with Nonmuscle-invasive Bladder Cancer: Do RDW and NLR Really Work?(2019) Senturk, Aykut Bugra; Ekici, Musa; Aydin, Cemil; Baykam, Mehmet Murat; Taş, Tuncay; Arda, Ersan; Çakıroğlu, BasriObjective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting laminapropria invasion in bladder cancer.Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were dividedinto those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocytecounts and RDW values were evaluated.Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease.RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4%probability of Ta disease.Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW canhelp clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.Öğe Reliability of thermocautery-assisted circumcision: retrospective analysis of circumcision performed voluntarily in countries of low socioeconomic status(SAGE Publications Inc., 2019) Çakıroğlu, Basri; Gozukucuk, Ali; Arda, Ersan; Taş, TuncayObjective: The objective of this study was to evaluate the reliability of thermocautery-assisted circumcision performed voluntarily in patients of poor countries. Material and methods: Between 2016 and 2019, 32,000 children aged 7 days to 17 years were circumcised in multiple countries. The patients’ urological examinations were done before the administration of local anaesthesia. Patients revealed to have undescended testicle, inguinal hernia, hypospadias, varicocele, penile rotation anomaly, epispadias and infection were not circumcised. All procedures were performed under local anaesthesia by using thermocautery. Afterwards, mucosa and skin were sutured using absorbable suture and the circumcised penis was dressed. Patients were instructed to remove the dressing after 3 days. Results: Bleeding, requiring surgical intervention and drug reactions were not observed. The most observed complication was mucosal oedema, which occurred in approximately one-quarter of patients (26%, 8320/32,000) and continued for 3–5 days after the surgery. The most serious complication was a trapped penis, which occurred in 25 patients (0.078%). In six (0.018%) cases, meatal stenosis developed. Wound infection developed in only 10 (0.03%) cases, through the formation of an aseptic environment. Penile adhesion was seen in 35 cases (0.1%) and improved with anti-inflammatory treatment without any surgical intervention. Conclusion: Thermocautery-assisted circumcision can be used as an effective, safe and useful technique with few complications and rapid healing rates. © The Author(s), 2019.Öğe Retrospective Analysis of Penile in Superficial Dorsal Vein Thrombosis(2020) Taş, Tuncay; Çakıroğlu, Basri; Arda, Ersan_Penile superficial venous throm-bosis is a rare and little-known benign genital condition. The largest series of penile superficial venous thrombosis cases in literature include 25 and 30 patients.Material and Methods_ A retrospective eva-luation was made of the data of 23 patients who were treated and followed up for a diagnosis of PMD in the Urology Outpatient Clinic between January 2009 and January 2018. Anamnesis, su-perficial vein color Doppler ultrasonography and routine laboratory analysis (i.e. blood count, elect-rolytes and coagulation tests) were applied to the patients. A conservative approach was provided the use of NSAIDs, anti-coagulant agents and to-pical Arnica Montana, and avoidance of the sexual activity. Follow-up examinations were made after 1, 3, 5, and 8 weeks and 3 months of treatment. Clinical improvement was evaluated.Results_ The age of the patients in the study was mean 42.4 ±11.12 years and median 44 ye-ars (range, 22-66 years). The mean BMI of the patients was 28.5±2.48 (range, 22.91-34.31). The mean period between the onset of symptoms and presentation was 9.35±13.42 days, median 4 days, and range, 1-60 days. On presentation, all the pa-tients had painless palpable cord symptoms. In 20 patients, the thrombotic vein could not be deter-mined externally. The diameter of the thrombosis was mean 3.09±1.04mm and median 3mm (range, 1.8–5). The diameter of the obstructed veins ran-ged from 1.3 to 4.7 mm. No pathological findings were determined in the standard laboratory tests of all 23 patients. The lesions were found to be pa-rallel to the sulcus below the coronal sulcus in 8 patients , and 15 patients had a cord-like lesion on the dorsal penis. The venous color Doppler ultra-sound results were similar for all the patients. No color filling and flow spectrum was observed inthe lumen of the superficial vein on color Doppler US. In the etiology, prolonged sexual activity was determined in 8 patients, prolonged masturbation in 5, the use of a vacuum erection device in 3, and 7 patients were idiopathic. Only 1 patient had a history of PMD deve-lopment. Conservative treatment was applied to 21 of the 23 cases. Thrombectomy was required in 2 cases. At follow-up examination, two recurrent episodes were observed.Conclusions_ Penile Mondor’s disease is rare, but causes notice-able anxiety in patients. The results of this study demonstrate the effect of trauma in the etiology. Patients generally recover with conservative treatment, and occasionally surgical treatment may be necessary_Öğe The role of serum acute phase reactant levels in the prediction of impacted ureteral stone(Kare Publishing, 2019) Hazar, Ismet Aydin; Taş, Tuncay; Gezmis, Cem Tugrul; Arda, Ersan; Cilesiz, Nusret Can; Çakıroğlu, BasriObjectives: The aim of this study was to investigate the determination of ureteral stone impaction using acute phase reactants. Methods: A total of 110 patients who had a single ureteral stone treated during a single month using medical expulsive therapy of tamsulosin 0.4 mg/day, diclofenac 75 mg upon analgesic requirement, and at least 3 liters fluid per day were evaluated prospectively. The patients underwent ureteroscopy and were divided into 2 groups according to the pres-ence or absence of impaction. The preoperative white blood cell (WBC) count, red blood cell distribution width (RDW), C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), mean platelet volume (MPV), and neutrophil-to-lymphocyte ratio (NLR) in the non-impacted stone group (Group 1; n=59) and the impacted group (Group 2; n=51) were statistically compared. Results: There was no statistically significant difference in terms of age, stone diameter, body mass index, grade of hy-dronephrosis, or stone localization between the 2 groups. The WBC, RDW, and MPV value differences were statistically significant between the groups (p=0.035, p=0.035, and p=0.005, respectively). An MPV cut-off value of 9.55 fL was de-fined in Group 2 with 66% sensitivity and 62% specificity for impaction. There was no statistically significant difference between the groups in CRP, ESR, or NLR values (p=0.44, p=0.76, p=0.54, respectively). Conclusion: Evaluation of serum MPV with a cut-off value of 9.55 fL may predict ureteral stone impaction. © 2019 by International Journal of Medical Biochemistry.Öğe Use of the UPOINT Classification in Turkish Chronic Prostatitis or Chronic Pelvic Pain Syndrome Patients(Elsevier Science Inc, 2016) Arda, Ersan; Çakıroğlu, Basri; Taş, Tuncay; Ekici, Sinan; Uyanik, Bekir SamiOBJECTIVE To determine the positive subdomain numbers and distribution of the UPOINT classification in chronic prostatitis and to compare the erectile dysfunction (ED) pattern. MATERIALS AND METHODS From 2008 to 2013, 839 patients with symptomatic chronic prostatitis or chronic pelvic pain syndrome were included in this study. The correlation between UPOINT domains and National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) total score, subscores, and the 5-item International Index of Erectile Function scores were evaluated retrospectively. RESULTS The mean patient age was calculated as 37.7 +/- 7.4 (range 21-65). The average total NIH-CPSI score was determined as 9.07 (range 1-40) and the average positive UPOINT subdomain number was determined as 2.87 +/- 0.32 (range 1-6). Subdomain patient numbers and rates were calculated as 529 urinary (63%), 462 psychosocial (55%), 382 organ specific (45%), 290 infection (34%), 288 neurological or systemic (34%), and 418 tenderness (skeletal muscle) (50%), respectively. It was determined that ED, determining the subdomain of sexual dysfunction in patients, was positive in a total of 326 (39.9%) patients, with 220 patients having mild (26.2%), 76 mild to moderate (9.1%), 19 moderate (2.3%), and 5 with severe (0.6%) ED. A statistically significant correlation was not determined between the 5-item International Index of Erectile Function score and UPOINT subdomain number and NIH-CPSI score. CONCLUSION It has been determined that although there is a strong and significant correlation between UPOINT classification and NIH-CPSI score in Turkish patients with chronic prostatitis or chronic pelvic pain syndrome, the inclusion of ED as an independent subdomain to the UPOINT classification is not statistically significant. (C) 2016 Elsevier Inc.
