Yazar "Erdem, Mehmet" seçeneğine göre listele

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    Comparison of popliteal anesthesia and spinal anesthesia in patients with the diabetic foot: Our clinical series
    (2021) Akdemir, Övünç; Tatar, Burak Ergün; Erdem, Mehmet; Köstekci, Hatice
    Aim: Surgery is of great importance in the treatment of diabetic foot. We aimed to compare unilateral spinal anesthesia and ultrasound-guided popliteal block procedures in patients diagnosed with a diabetic foot ulcer. Materials and Methods: In this study, we included 54 patients diagnosed with diabetic foot ulcers in our hospital between September 2010 and December 2012. The patients were randomly divided into two groups of 27 patients each: Group I (Spinal group) and Group II (Popliteal group). Spinal anesthesia was performed in Group I, whereas ultrasound-guided popliteal block was performed in Group II. During and after the anesthesia, the total isotonic fluid given, average patient and surgeon satisfaction score, and length of hospital stay were evaluated. Results: In Group I, the average length of hospital stay was 6.07 ± 1.2 days, the total isotonic fluid given was 1832.2 ± 280.7 ml, and the average patient and surgeon satisfaction score was 2.44 ± 0.5. In Group II, the average length of hospital stay was 6.5 ± 1.04 days, the total isotonic fluid given was 731.11 ± 130.2 ml, and the average patient and surgeon satisfaction score were 3. In addition, in Group I, 9 patients had bradycardia and 12 patients had hypotension and nausea. The findings of the study indicate a statistically significant difference in terms of the total isotonic fluid given and average patient and surgeon satisfaction scores (p < 0.05). However, no statistically significant difference was observed in terms of hospital stay (p > 0.05). Conclusion: In conclusion, we believe that ultrasound-guided popliteal block provides more reliable and efficient analgesia than spinal anesthesia in patients with diabetic foot ulcers.
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    The Effect of Ceruloplasmin Against Ischemia-Reperfusion Injury in Epigastric Island Flap in Rats
    (Academic Press Inc., 2021) Seyid, Mircafer; Tiftikcioglu, Yigit; Erdem, Mehmet; Akdemir, Övünç; Tatar, Burak Ergün; Uyanıkgil, Yigit; Ercan, Gülinnaz
    Background: Flap surgery is frequently used in plastic surgery to close tissue defects. Ischemia-reperfusion (I/R) injury is a significant problem resulting in partial or total flap necrosis. This study aimed to investigate the effect of ceruloplasmin on I/R injury in epigastric island flaps in rats. Material and method: A total of 32 male Sprague-Dawley rats were divided into four groups with eight rats in each group: The flap was not elevated in Group I; the flap was elevated without ischemia or any application in Group II, after the intraperitoneal saline and ceruloplasmin application the flaps were elevated and ischemia was created in group III-IV, respectively. Bilateral epigastric artery flap was elevated in all groups except Group I. After 6 h of ischemia, the flap was reperfused and inset. Samples were taken from the right and left side of the flap area in other groups at the postoperative 24th h for biochemical analysis (catalase and malondialdehyde-MDA) and the seventh postoperative day for histopathological analysis (Modified Verhofstad score and epidermal thicknesses), respectively. Image analysis for necrosis areas was performed on photos taken on the 7th d. Results: Catalase level was significantly higher in Group IV.(0.15 ± 0.04 U/mg protein) (P < 0.05) Necrosis area percentage(14.4% ± 3.3%),MDA(3.6 ± 0.9 nmol/mg protein), edema(3), necrosis(2.75), and polymorphonuclear leukocyte infiltration(2.87) scores were significantly higher in group III.(P < 0.05). Fibroblast proliferation, collagen density (0.25), vascular density (0.25) scores and epidermal thickness (15.68 µm,) was significantly lower in group III. (P < 0.05) Conclusions: Our study demonstrated that ceruloplasmin application before ischemia reduced I/R injury in epigastric island flaps in rats. © 2021 Elsevier Inc.