Hazar, Ismet AydinTaş, TuncayGezmis, Cem TugrulArda, ErsanCilesiz, Nusret CanÇakıroğlu, Basri2025-03-262025-03-2620192587-236210.14744/ijmb.2019.205922-s2.0-85168942620https://doi.org/10.14744/ijmb.2019.20592https://search.trdizin.gov.tr/tr/yayin/detay/331817https://hdl.handle.net/20.500.14704/776Objectives: The aim of this study was to investigate the determination of ureteral stone impaction using acute phase reactants. Methods: A total of 110 patients who had a single ureteral stone treated during a single month using medical expulsive therapy of tamsulosin 0.4 mg/day, diclofenac 75 mg upon analgesic requirement, and at least 3 liters fluid per day were evaluated prospectively. The patients underwent ureteroscopy and were divided into 2 groups according to the pres-ence or absence of impaction. The preoperative white blood cell (WBC) count, red blood cell distribution width (RDW), C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), mean platelet volume (MPV), and neutrophil-to-lymphocyte ratio (NLR) in the non-impacted stone group (Group 1; n=59) and the impacted group (Group 2; n=51) were statistically compared. Results: There was no statistically significant difference in terms of age, stone diameter, body mass index, grade of hy-dronephrosis, or stone localization between the 2 groups. The WBC, RDW, and MPV value differences were statistically significant between the groups (p=0.035, p=0.035, and p=0.005, respectively). An MPV cut-off value of 9.55 fL was de-fined in Group 2 with 66% sensitivity and 62% specificity for impaction. There was no statistically significant difference between the groups in CRP, ESR, or NLR values (p=0.44, p=0.76, p=0.54, respectively). Conclusion: Evaluation of serum MPV with a cut-off value of 9.55 fL may predict ureteral stone impaction. © 2019 by International Journal of Medical Biochemistry.eninfo:eu-repo/semantics/openAccessImpactedmean platelet volumered blood cell distribution widthureteral stonewhite blood cellArticle1063Q41023318172